Pastilles DMXE 40 mg (désoxyméthoxétamine)

DMXE (Deoxymethoxetamine) 40mg Pellets – Scientific Product Documentation

🔬Spécifications chimiques

DMXE (2′-Oxo-PCE-d10) is a research chemical belonging to the arylcyclohexylamine class, structurally related to MXE (methoxetamine) and ketamine. These pellets are formulated for precise scientific research.

Paramètres principaux :

• Nom IUPAC : 2-(3,4-diméthylphényl)-2-(éthylamino)cyclohexanone

• Formule moléculaire : C₁₆H₂₃NO

• Poids moléculaire : 245.36 g/mol

• Pureté : ≥98% (GC-MS analysis)

• Shape : Round, 4mm diameter pellets

• Color : Light beige to white

• Solubilité : 15 mg/ml in water (at 25°C)

🧪Applications scientifiques

1. Neuropharmacological research :

   • NMDA receptor antagonism studies

   • Sigma-1 receptor interaction assays

2. Neurosciences comportementales :

   • Effects on learning behavior in laboratory animals

   • Dose-dependent dissociative effects

3. Psychopharmacologie :

   • Comparative studies with related dissociatives

   • Research into neuroplastic effects

⚖️Recommended Research Protocols

Experimental guidelines:

*Note: Non-linear pharmacokinetics above 25 mg/kg*

⚠️Safety Profile & Risk Management

1. données toxicologiques :

   • DL₅₀ (rat, voie orale) : 320 mg/kg

   • NOAEL: 5 mg/kg/day (7-day study)

2. Spectre des effets secondaires :

   • <10 mg: Subtle behavioral effects

   • 10-30 mg: Motor incoordination

   • 30 mg: Potential respiratory depression

3. Interactions critiques :

   • Dangereux : Opioids, GABA-ergics

   • Risqué : Stimulants, MAO inhibitors

📊Quality Control & Analytical Data

• HPLC purity : 98.5% (C18 column, 70:30 H₂O:MeCN)

• Uniformity : ±5% weight deviation (n=20 pellets)

• Disintegration time : <15 minutes (in simultaneous gastric juice)

• Données de stabilité :

  • Shelf life: 24 months at 15-25°C

  • Moisture sensitivity: <0.5% weight gain (93% RH)

❓Frequently Asked Research Questions

Q1 : Quel est le mécanisme d'action ?
A: Primary NMDA receptor antagonism with secondary dopamine reuptake inhibition.

Q2: How does the potency compare to ketamine?
A: ~0.6x the potency of ketamine but a longer half-life (4-6 hours).

Q3: Are there any neurotoxic risks?
A: Olney’s lesions were not observed at <50 mg/kg (rat study).

Q4: What is the optimal storage method?
A: In the original packaging at 15-25°C, protected from moisture.

📌Limites de la recherche

• Limited data on chronic administration

• Unknown effects on glutamate transmission

• Variable biotransformation between species

🔍Conclusion for Researchers

DMXE 40mg pellets offer a standardized formulation for precise dissociative research, with consistent dose delivery and good stability. The pellet form facilitates quantitative administration in animal studies.

Scientific disclaimer: This product is intended solely for in vitro research and authorized preclinical studies. Not for human use. All experiments must comply with applicable ethical guidelines and local regulations. Please be aware of the special status of psychoactive research substances in your jurisdiction.