{"id":24961,"date":"2025-10-20T17:43:53","date_gmt":"2025-10-20T17:43:53","guid":{"rendered":"https:\/\/researchchemicalhub.com\/?post_type=product&#038;p=24961"},"modified":"2025-10-28T22:38:22","modified_gmt":"2025-10-28T22:38:22","slug":"o-dsmt-50mg-pellets","status":"publish","type":"product","link":"https:\/\/researchchemicalhub.com\/en\/shop\/o-dsmt\/o-dsmt-50mg-pellets\/","title":{"rendered":"O-DSMT 50mg Pellets"},"content":{"rendered":"<h1 data-start=\"399\" data-end=\"488\"><strong data-start=\"401\" data-end=\"488\">O-DSMT (O-Desmethyltramadol) \u2013 Scientific Information and Analytical Overview<\/strong><\/h1>\n<p data-start=\"490\" data-end=\"739\"><strong data-start=\"490\" data-end=\"512\">Meta description:<\/strong><br data-start=\"512\" data-end=\"515\" \/>O-DSMT (O-Desmethyltramadol) is a research drug and a pharmacologically active metabolite of tramadol. Learn more about the chemical structure, mechanism of action, scientific relevance, and safety aspects of O-DSMT.<\/p>\n<hr data-start=\"741\" data-end=\"744\" \/>\n<h2 data-start=\"746\" data-end=\"762\"><strong data-start=\"749\" data-end=\"762\">Introduction<\/strong><\/h2>\n<p data-start=\"764\" data-end=\"1036\"><strong data-start=\"764\" data-end=\"796\">O-Desmethyltramadol (O-DSMT)<\/strong> is a <strong data-start=\"804\" data-end=\"831\">synthetic compound<\/strong> which belongs to the group of <strong data-start=\"861\" data-end=\"883\">opioid analgesics<\/strong>. It is the <strong data-start=\"895\" data-end=\"930\">active metabolite of tramadol<\/strong>, an analgesic used worldwide for the treatment of moderate to severe pain.<\/p>\n<p data-start=\"1038\" data-end=\"1395\">O-DSMT is formed in the body when tramadol is metabolized by the liver via the enzyme CYP2D6. This metabolite is <strong data-start=\"1154\" data-end=\"1221\">responsible for a large part of the analgesic effect<\/strong> of tramadol. In a research context, O-DSMT is being studied to <strong data-start=\"1287\" data-end=\"1348\">pharmacological action, receptor activity and safety<\/strong> to better understand opioid compounds.<\/p>\n<p data-start=\"1397\" data-end=\"1601\">O-DSMT is sometimes mentioned in scientific literature on <strong data-start=\"1460\" data-end=\"1498\">new psychoactive substances (NPS)<\/strong> and <strong data-start=\"1502\" data-end=\"1529\">forensic toxicology<\/strong>, but it is <strong data-start=\"1543\" data-end=\"1600\">not approved for human use or consumption<\/strong>.<\/p>\n<hr data-start=\"1603\" data-end=\"1606\" \/>\n<h2 data-start=\"1608\" data-end=\"1653\"><strong data-start=\"1611\" data-end=\"1653\">Key Features<\/strong><\/h2>\n<div class=\"_tableContainer_1rjym_1\">\n<div class=\"group _tableWrapper_1rjym_13 flex w-fit flex-col-reverse\" tabindex=\"-1\">\n<table class=\"w-fit min-w-(--thread-content-width)\" data-start=\"1655\" data-end=\"2176\">\n<thead data-start=\"1655\" data-end=\"1692\">\n<tr data-start=\"1655\" data-end=\"1692\">\n<th data-start=\"1655\" data-end=\"1672\" data-col-size=\"sm\"><strong data-start=\"1657\" data-end=\"1671\">Characteristic<\/strong><\/th>\n<th data-start=\"1672\" data-end=\"1692\" data-col-size=\"md\"><strong data-start=\"1674\" data-end=\"1690\">Description<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody data-start=\"1732\" data-end=\"2176\">\n<tr data-start=\"1732\" data-end=\"1776\">\n<td data-start=\"1732\" data-end=\"1753\" data-col-size=\"sm\"><strong data-start=\"1734\" data-end=\"1752\">Full name<\/strong><\/td>\n<td data-start=\"1753\" data-end=\"1776\" data-col-size=\"md\">O-Desmethyltramadol<\/td>\n<\/tr>\n<tr data-start=\"1777\" data-end=\"1814\">\n<td data-start=\"1777\" data-end=\"1801\" data-col-size=\"sm\"><strong data-start=\"1779\" data-end=\"1800\">Chemical formula<\/strong><\/td>\n<td data-start=\"1801\" data-end=\"1814\" data-col-size=\"md\">C\u2081\u2085H\u2082\u2083NO\u2082<\/td>\n<\/tr>\n<tr data-start=\"1815\" data-end=\"1851\">\n<td data-start=\"1815\" data-end=\"1835\" data-col-size=\"sm\"><strong data-start=\"1817\" data-end=\"1834\">Molar mass<\/strong><\/td>\n<td data-col-size=\"md\" data-start=\"1835\" data-end=\"1851\">249.35 g\/mol<\/td>\n<\/tr>\n<tr data-start=\"1852\" data-end=\"1919\">\n<td data-start=\"1852\" data-end=\"1875\" data-col-size=\"sm\"><strong data-start=\"1854\" data-end=\"1874\">Chemical class<\/strong><\/td>\n<td data-start=\"1875\" data-end=\"1919\" data-col-size=\"md\">Synthetic opioid; tramadol metabolite<\/td>\n<\/tr>\n<tr data-start=\"1920\" data-end=\"1979\">\n<td data-start=\"1920\" data-end=\"1950\" data-col-size=\"sm\"><strong data-start=\"1922\" data-end=\"1949\">Pharmacological action<\/strong><\/td>\n<td data-col-size=\"md\" data-start=\"1950\" data-end=\"1979\">\u03bc-opioid receptor agonist<\/td>\n<\/tr>\n<tr data-start=\"1980\" data-end=\"2042\">\n<td data-start=\"1980\" data-end=\"1997\" data-col-size=\"sm\"><strong data-start=\"1982\" data-end=\"1996\">Application<\/strong><\/td>\n<td data-col-size=\"md\" data-start=\"1997\" data-end=\"2042\">Pharmacological and toxicological research<\/td>\n<\/tr>\n<tr data-start=\"2043\" data-end=\"2097\">\n<td data-start=\"2043\" data-end=\"2054\" data-col-size=\"sm\"><strong data-start=\"2045\" data-end=\"2053\">Form<\/strong><\/td>\n<td data-col-size=\"md\" data-start=\"2054\" data-end=\"2097\">Reference substance for laboratory analysis<\/td>\n<\/tr>\n<tr data-start=\"2098\" data-end=\"2176\">\n<td data-start=\"2098\" data-end=\"2122\" data-col-size=\"sm\"><strong data-start=\"2100\" data-end=\"2121\">Legal status<\/strong><\/td>\n<td data-col-size=\"md\" data-start=\"2122\" data-end=\"2176\">Regulated under opioid laws in many countries<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<hr data-start=\"2178\" data-end=\"2181\" \/>\n<h2 data-start=\"2183\" data-end=\"2238\"><strong data-start=\"2186\" data-end=\"2238\">Scientific Relevance and Research Value<\/strong><\/h2>\n<ul data-start=\"2240\" data-end=\"3199\">\n<li data-start=\"2240\" data-end=\"2514\">\n<p data-start=\"2242\" data-end=\"2514\"><strong data-start=\"2242\" data-end=\"2270\">Pharmacological research<\/strong><br data-start=\"2270\" data-end=\"2273\" \/>O-DSMT is used to <strong data-start=\"2303\" data-end=\"2335\">mechanisms of pain relief<\/strong> Better understand and compare it with other opioid agonists. This helps researchers gain insight into receptor selectivity, metabolic pathways, and structural variations.<\/p>\n<\/li>\n<li data-start=\"2516\" data-end=\"2769\">\n<p data-start=\"2518\" data-end=\"2769\"><strong data-start=\"2518\" data-end=\"2544\">Toxicological analysis<\/strong><br data-start=\"2544\" data-end=\"2547\" \/>In forensic and clinical toxicology laboratories, O-DSMT is used as <strong data-start=\"2629\" data-end=\"2663\">reference or calibration substance<\/strong> to analyze biological samples (such as blood or urine) for the presence of tramadol metabolites.<\/p>\n<\/li>\n<li data-start=\"2771\" data-end=\"2970\">\n<p data-start=\"2773\" data-end=\"2970\"><strong data-start=\"2773\" data-end=\"2804\">Analytical characterization<\/strong><br data-start=\"2804\" data-end=\"2807\" \/>The material is examined using techniques such as <strong data-start=\"2866\" data-end=\"2892\">LC-MS\/MS, GC-MS and NMR<\/strong> to enable identification and quantification in research samples.<\/p>\n<\/li>\n<li data-start=\"2972\" data-end=\"3199\">\n<p data-start=\"2974\" data-end=\"3199\"><strong data-start=\"2974\" data-end=\"3013\">Regulatory and safety studies<\/strong><br data-start=\"3013\" data-end=\"3016\" \/>O-DSMT helps develop detection protocols for <strong data-start=\"3080\" data-end=\"3118\">new psychoactive substances (NPS)<\/strong> and in the assessment of risks to public health and potential for abuse.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"3201\" data-end=\"3204\" \/>\n<h2 data-start=\"3206\" data-end=\"3264\"><strong data-start=\"3209\" data-end=\"3264\">Laboratory Use (For Research Only)<\/strong><\/h2>\n<blockquote data-start=\"3266\" data-end=\"3480\">\n<p data-start=\"3268\" data-end=\"3480\">\u26a0\ufe0f <strong data-start=\"3271\" data-end=\"3286\">Important:<\/strong><br data-start=\"3286\" data-end=\"3289\" \/>O-DSMT is <strong data-start=\"3301\" data-end=\"3356\">intended for scientific research only<\/strong> in authorized laboratories.<br data-start=\"3387\" data-end=\"3390\" \/>It is <strong data-start=\"3399\" data-end=\"3480\">not intended for human consumption, self-medication or recreational use.<\/strong><\/p>\n<\/blockquote>\n<ol data-start=\"3482\" data-end=\"4188\">\n<li data-start=\"3482\" data-end=\"3702\">\n<p data-start=\"3485\" data-end=\"3512\"><strong data-start=\"3485\" data-end=\"3510\">Storage and Stability<\/strong><\/p>\n<ul data-start=\"3516\" data-end=\"3702\">\n<li data-start=\"3516\" data-end=\"3577\">\n<p data-start=\"3518\" data-end=\"3577\">Store in a closed container, dry and cool (2\u20138 \u00b0C).<\/p>\n<\/li>\n<li data-start=\"3581\" data-end=\"3624\">\n<p data-start=\"3583\" data-end=\"3624\">Protect from light, moisture and air.<\/p>\n<\/li>\n<li data-start=\"3628\" data-end=\"3702\">\n<p data-start=\"3630\" data-end=\"3702\">Use only within institutions with valid research permits.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"3704\" data-end=\"3931\">\n<p data-start=\"3707\" data-end=\"3735\"><strong data-start=\"3707\" data-end=\"3733\">Analytical Application<\/strong><\/p>\n<ul data-start=\"3739\" data-end=\"3931\">\n<li data-start=\"3739\" data-end=\"3839\">\n<p data-start=\"3741\" data-end=\"3839\">Used as a standard in LC-MS and GC-MS analysis to identify tramadol metabolites.<\/p>\n<\/li>\n<li data-start=\"3843\" data-end=\"3931\">\n<p data-start=\"3845\" data-end=\"3931\">Suitable for methodological validation in toxicological or pharmaceutical studies.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"3933\" data-end=\"4188\">\n<p data-start=\"3936\" data-end=\"3972\"><strong data-start=\"3936\" data-end=\"3970\">Safety in the Laboratory<\/strong><\/p>\n<ul data-start=\"3976\" data-end=\"4188\">\n<li data-start=\"3976\" data-end=\"4042\">\n<p data-start=\"3978\" data-end=\"4042\">Always wear gloves, safety glasses and a lab coat.<\/p>\n<\/li>\n<li data-start=\"4046\" data-end=\"4097\">\n<p data-start=\"4048\" data-end=\"4097\">Avoid contact with skin, eyes or mucous membranes.<\/p>\n<\/li>\n<li data-start=\"4101\" data-end=\"4188\">\n<p data-start=\"4103\" data-end=\"4188\">Dispose of waste in accordance with chemical safety regulations and national regulations.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<hr data-start=\"4190\" data-end=\"4193\" \/>\n<h2 data-start=\"4195\" data-end=\"4223\"><strong data-start=\"4198\" data-end=\"4223\">Legal Information<\/strong><\/h2>\n<p data-start=\"4225\" data-end=\"4501\">O-DSMT is covered by the <strong data-start=\"4270\" data-end=\"4298\">Opium Act<\/strong> or similar arrangements for opioid substances.<br data-start=\"4348\" data-end=\"4351\" \/>Researchers and laboratories must <strong data-start=\"4386\" data-end=\"4414\">prior consent<\/strong> obtain for the storage, transport or use of O-DSMT in a research context.<\/p>\n<p data-start=\"4503\" data-end=\"4674\">The fabric may <strong data-start=\"4515\" data-end=\"4551\">not be sold or used<\/strong> outside of accredited research institutions. Unauthorized possession or use may result in <strong data-start=\"4642\" data-end=\"4673\">criminal prosecution<\/strong>.<\/p>\n<hr data-start=\"4676\" data-end=\"4679\" \/>\n<h2 data-start=\"4681\" data-end=\"4713\"><strong data-start=\"4684\" data-end=\"4713\">Frequently Asked Questions (FAQ)<\/strong><\/h2>\n<p data-start=\"4715\" data-end=\"4934\"><strong data-start=\"4715\" data-end=\"4745\">1\ufe0f\u20e3 What exactly is O-DSMT?<\/strong><br data-start=\"4745\" data-end=\"4748\" \/>O-DSMT is the <strong data-start=\"4761\" data-end=\"4796\">active metabolite of tramadol<\/strong>, formed in the body after tramadol intake. In research settings, it is used to study the pharmacology of opioids.<\/p>\n<p data-start=\"4936\" data-end=\"5163\"><strong data-start=\"4936\" data-end=\"4961\">2\ufe0f\u20e3 Is O-DSMT legal?<\/strong><br data-start=\"4961\" data-end=\"4964\" \/>The legal status varies by country. In most European countries, O-DSMT falls under opioid legislation, which means it can only be used for scientific or forensic purposes.<\/p>\n<p data-start=\"5165\" data-end=\"5433\"><strong data-start=\"5165\" data-end=\"5246\">3\ufe0f\u20e3 Can O-DSMT be used for personal use or microdosing?<\/strong><br data-start=\"5246\" data-end=\"5249\" \/>No. O-DSMT is <strong data-start=\"5264\" data-end=\"5311\">not approved for human consumption<\/strong> and may only be used in a controlled laboratory environment. Unauthorized use is dangerous and illegal.<\/p>\n<hr data-start=\"5435\" data-end=\"5438\" \/>\n<h2 data-start=\"5440\" data-end=\"5480\"><strong data-start=\"5443\" data-end=\"5480\">References and Further Information<\/strong><\/h2>\n<ul data-start=\"5482\" data-end=\"5840\">\n<li data-start=\"5482\" data-end=\"5639\">\n<p data-start=\"5484\" data-end=\"5639\">European Monitoring Center for Drugs and Drug Addiction (EMCDDA): <em data-start=\"5550\" data-end=\"5637\">Report on New Psychoactive Substances (NPS) \u2013 Opioids and tramadol derivatives.<\/em><\/p>\n<\/li>\n<li data-start=\"5640\" data-end=\"5737\">\n<p data-start=\"5642\" data-end=\"5737\">National Institute on Drug Abuse (NIDA): <em data-start=\"5683\" data-end=\"5735\">Synthetic Opioids and Emerging Analogue Compounds.<\/em><\/p>\n<\/li>\n<li data-start=\"5738\" data-end=\"5840\">\n<p data-start=\"5740\" data-end=\"5840\">Forensic Toxicology Journals: <em data-start=\"5770\" data-end=\"5838\">Analytical Identification and Pharmacology of O-Desmethyltramadol.<\/em><\/p>\n<\/li>\n<\/ul>\n<p><a href=\"https:\/\/researchchemicalhub.com\/en\/shop\/iboga-ibogaine\/buy-ibogaine-hcl-online\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Buy Ibogaine HCL <\/span><\/span><\/a><a href=\"https:\/\/researchchemicalhub.com\/en\/shop\/iboga-ibogaine\/iboga-root-bark\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Iboga root bark <\/span><\/span><\/a><a href=\"https:\/\/researchchemicalhub.com\/en\/shop\/lysergamides\/1cp-lsd\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1cP-LSD 150 MCG Art Blotters <\/span><\/span><\/a><a href=\"https:\/\/researchchemicalhub.com\/en\/shop\/lysergamides\/1v-lsd-150-mcg-blotters\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1V-LSD 150 MCG Blotters <\/span><\/span><\/a><a href=\"https:\/\/researchchemicalhub.com\/en\/shop\/2-cmc-pellets\/2-cmc-kopen\/2-cmc-kopen\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2-CMC 250mg pellets<\/span><\/span><\/a><\/p>","protected":false},"excerpt":{"rendered":"<h3><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">O-DSMT properties<\/span><\/span><\/h3>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Synonym: <\/span><\/span><\/strong> <i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">O-Desmethyltramadol, 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol <\/span><\/span><\/i><br \/>\n<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">CAS Number:<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> 80456-81-1 <\/span><\/span><br \/>\n<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Formula: <\/span><\/span><\/strong> <span title=\"Carbon\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C <\/span><\/span><\/span><sub><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">15 <\/span><\/span><\/sub><span title=\"Hydrogen\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">H <\/span><\/span><\/span><sub><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">23 <\/span><\/span><\/sub><span title=\"Nitrogen\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">N <\/span><\/span><\/span><span title=\"Oxygen\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">O <\/span><\/span><\/span><sub><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2 <\/span><\/span><\/sub><br \/>\n<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Molar mass:<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> 249.354 g\/mol <\/span><\/span><br \/>\n<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Purity:<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0&gt;97%<\/span><\/span><\/p>","protected":false},"featured_media":28581,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[82],"product_cat":[337,420,336,324],"product_tag":[326,727,725,728,726,729,730],"class_list":{"0":"post-24961","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-research-chemical","7":"product_cat-o-dsmt","8":"product_cat-o-dsmt-pellets","9":"product_cat-overig","10":"product_cat-pellets-for-pellet","11":"product_tag-nl","12":"product_tag-o-dsmt-ervaringen","13":"product_tag-o-dsmt","14":"product_tag-o-dsmt-bestellen","15":"product_tag-o-dsmt-kopen","16":"product_tag-o-dsmt-psychonaut","17":"product_tag-what-is-o-dsmt","19":"first","20":"instock","21":"taxable","22":"shipping-taxable","23":"purchasable","24":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product\/24961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/comments?post=24961"}],"version-history":[{"count":7,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product\/24961\/revisions"}],"predecessor-version":[{"id":27709,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product\/24961\/revisions\/27709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/media\/28581"}],"wp:attachment":[{"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/media?parent=24961"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product_brand?post=24961"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product_cat?post=24961"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalhub.com\/en\/wp-json\/wp\/v2\/product_tag?post=24961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}