 
				 
				4C-E
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Introduction
4C-E (full chemical name: 1-(2,5-dimethoxy-4-ethylphenyl)butan-2-amine) belongs to the 4C class of substituted phenethylamines—compounds with an extended α-ethyl side branch and methoxy groups at positions 2 and 5 of the phenyl ring. Because 4C-E is relatively unknown, there is limited publication on it, but it is attracting interest in chemical and pharmacological research communities investigating structure–activity relationships. 4C E
If you search for “ buy 4C-E ”, this description will help you understand what 4C-E is, what is known, and how it is treated scientifically.
Key Features
| Feature | Description | 
|---|---|
| Chemical Structure | Contains two methoxy groups (positions 2 and 5) and an ethyl substituent at position 4 of the phenyl ring | 
| α-Ethyl Side Branch | Belongs to the 4C family (ie α-ethyl phenethylamines) | 
| Receptor interaction | Probably a partial agonist at serotonin 5-HT₂A receptors (analogous to other 4C compounds) | 
| Research status | Little empirical research; mainly theoretical, computational or anecdotal data | 
| Physical & Handling Properties | Must be handled under controlled laboratory conditions with attention to purity, stability and storage | 
Benefits / Potential Value
- Understanding Structure–Activity : 4C-E can serve as a comparator to understand how α-ethyl substitution (as opposed to α-methyl in 2C analogs) affects potency, receptor efficacy, metabolic stability, and side effects. 
- Novelty & Exploration : Because it is less documented, studies of 4C-E may reveal unexpected behavior, binding affinities, or metabolites. 
- Scientific Interest : It broadens the spectrum of research on substituted phenethylamines and may contribute to medicinal chemistry, neuropharmacology or computational modeling. 
- Selected Studies : In controlled settings, 4C-E can help clarify which structural positions have a major influence on psychedelic potency or safety margins. 
How to Use / Handling Guidelines
Important Note : The following is intended for authorized researchers and qualified chemists working within legal frameworks. It is not intended as advice for unauthorized or recreational use.
- Purity & Verification - Use high purity sample (≥ 98%) and certificate of analysis. 
- Confirm identity by NMR, MS, HPLC, or other analytical methods. 
 
- Storage - Store under an inert, dry environment (eg amber glass vials under nitrogen or argon). 
- Keep at a low temperature (eg, −20 °C or refrigeration) to minimize decomposition. 4C E 
 
- Weighing & Solution Preparation - Use a microbalance and weigh in a controlled atmosphere (glovebox or dry room) if the substance is hygroscopic. 
- Dissolve in suitable solvents (eg DMSO, methanol) for stock solutions, ensuring complete dissolution occurs before further dilution. 
 
- Dosage (Experimental / Comparative Use) - Start with minimal test doses (microgram scale) for receptor binding assays or in vitro testing. 
- Work with strict controls, repeated measurements, and use blanks/placebos. 
 
- Safety / Control - Work in fume hood or containment system to avoid inhalation or skin exposure. 
- Wear gloves, safety glasses, lab coat. 
- Dispose of waste in accordance with institutional and regulatory chemical safety procedures. 
 
Frequently Asked Questions (FAQ)
1. What is the difference between 4C-E and 2C analogs?
 4C-E has an α-ethyl side branch instead of an α-methyl (as in the 2C family). This extension often reduces potency but can improve metabolic stability.
2. Is it legal to buy 4C-E (“buy 4C-E”)?
 The legality of 4C-E (and the ability to buy 4C-E ) depends entirely on your jurisdiction. In many countries, substituted phenethylamines or their analogues are subject to analogue laws or are classified as prohibited substances. Always check local laws before purchasing or experimenting with this substance.
3. Are there any documented human trials or effects?
 No, there are no properly controlled human trials or clinical data for 4C-E. Most available information is speculative, anecdotal, or based on computational models and analogies. Buy 4mmc, buy benzocaine powder, buy fentanyl
Introduction
4C-E (full chemical name: 1-(2,5-dimethoxy-4-ethylphenyl)butan-2-amine) belongs to the 4C class of substituted phenethylamines—compounds with an extended α-ethyl side branch and methoxy groups at positions 2 and 5 of the phenyl ring. Because 4C-E is relatively unknown, there is limited publication on it, but it is attracting interest in chemical and pharmacological research communities investigating structure–activity relationships. 4C E
If you search for “ buy 4C-E ”, this description will help you understand what 4C-E is, what is known, and how it is treated scientifically.
Key Features
| Feature | Description | 
|---|---|
| Chemical Structure | Contains two methoxy groups (positions 2 and 5) and an ethyl substituent at position 4 of the phenyl ring | 
| α-Ethyl Side Branch | Belongs to the 4C family (ie α-ethyl phenethylamines) | 
| Receptor interaction | Probably a partial agonist at serotonin 5-HT₂A receptors (analogous to other 4C compounds) | 
| Research status | Little empirical research; mainly theoretical, computational or anecdotal data | 
| Physical & Handling Properties | Must be handled under controlled laboratory conditions with attention to purity, stability and storage | 
Benefits / Potential Value
- Understanding Structure–Activity : 4C-E can serve as a comparator to understand how α-ethyl substitution (as opposed to α-methyl in 2C analogs) affects potency, receptor efficacy, metabolic stability, and side effects. 
- Novelty & Exploration : Because it is less documented, studies of 4C-E may reveal unexpected behavior, binding affinities, or metabolites. 
- Scientific Interest : It broadens the spectrum of research on substituted phenethylamines and may contribute to medicinal chemistry, neuropharmacology or computational modeling. 
- Selected Studies : In controlled settings, 4C-E can help clarify which structural positions have a major influence on psychedelic potency or safety margins. 
How to Use / Handling Guidelines
Important Note : The following is intended for authorized researchers and qualified chemists working within legal frameworks. It is not intended as advice for unauthorized or recreational use.
- Purity & Verification - Use high purity sample (≥ 98%) and certificate of analysis. 
- Confirm identity by NMR, MS, HPLC, or other analytical methods. 
 
- Storage - Store under an inert, dry environment (eg amber glass vials under nitrogen or argon). 
- Keep at a low temperature (eg, −20 °C or refrigeration) to minimize decomposition. 4C E 
 
- Weighing & Solution Preparation - Use a microbalance and weigh in a controlled atmosphere (glovebox or dry room) if the substance is hygroscopic. 
- Dissolve in suitable solvents (eg DMSO, methanol) for stock solutions, ensuring complete dissolution occurs before further dilution. 
 
- Dosage (Experimental / Comparative Use) - Start with minimal test doses (microgram scale) for receptor binding assays or in vitro testing. 
- Work with strict controls, repeated measurements, and use blanks/placebos. 
 
- Safety / Control - Work in fume hood or containment system to avoid inhalation or skin exposure. 
- Wear gloves, safety glasses, lab coat. 
- Dispose of waste in accordance with institutional and regulatory chemical safety procedures. 
 
Frequently Asked Questions (FAQ)
1. What is the difference between 4C-E and 2C analogs?
 4C-E has an α-ethyl side branch instead of an α-methyl (as in the 2C family). This extension often reduces potency but can improve metabolic stability.
2. Is it legal to buy 4C-E (“buy 4C-E”)?
 The legality of 4C-E (and the ability to buy 4C-E ) depends entirely on your jurisdiction. In many countries, substituted phenethylamines or their analogues are subject to analogue laws or are classified as prohibited substances. Always check local laws before purchasing or experimenting with this substance.
3. Are there any documented human trials or effects?
 No, there are no properly controlled human trials or clinical data for 4C-E. Most available information is speculative, anecdotal, or based on computational models and analogies. Buy 4mmc, buy benzocaine powder, buy fentanyl
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